The Characteristics of Patients with Lymphadenopathy Undergoing Fine-Needle Aspiration Biopsy at a Tertiary Hospital in Surabaya, Indonesia
Characteristics of Patients with Lymphadenopathy Undergoing Fine-Needle Aspiration Biopsy
DOI:
https://doi.org/10.59747/smjidisurabaya.v3i2.122Keywords:
Cancer, Fine-needle aspiration biopsy, LymphadenopathyAbstract
Background: Lymphadenopathy is a frequently observed clinical presentation in outpatient settings. Lymphadenopathy may arise from various etiologies, such as reactive lymphoid hyperplasia, infectious diseases, or malignant neoplasms. The first choice to diagnose superficial lymphadenopathy is usually fine needle aspiration biopsy (FNAB). The role of fine-needle aspiration biopsy (FNAB) in diagnosing superficial lymphadenopathy is to identify the specific type and potential origin of metastatic malignancy within the lymph node.
Objective: This study aims to describe the characteristics of patients with lymphadenopathy who underwent fine-needle aspiration biopsy at Dr. Soetomo General Hospital.
Material and Method: This is a descriptive retrospective study using secondary data from patients with lymphadenopathy who underwent fine-needle aspiration biopsy at the Laboratory of Anatomical Pathology of Dr. Soetomo General Hospital (January 2019-December 2019).
Result: This study included 945 patients consisting of 410 males (43,4%) and 535 females (56,6%). Out of 945 cases, 499 (52.8%) were diagnosed as non-malignant lesions, 428 (45.3%) as malignant lesions, 11 (1.2%) as atypical cells, and 7 (0.7%) as inadequate.
Conclusion: The most common patients with lymphadenopathy at Dr. Soetomo General Academic Hospital Surabaya were female patients aged 41-60, with mostly non-malignant lesions.
References
Abbott, M., Jiang, L., Youssef, B., Siddiqi, A. and Nassar, A. (2022) Reliability of lymphoma diagnosis using combined cytologic preparations and core needle biopsy: A single-center analysis. Cytojournal, 19(1).
Andhika, D., Handayati, A. and Woelansari, E.D. (2023) Diagnostic Test Fine Needle Aspiration Biopsy (FNAB) Examination on Gold Standard Histopathological Tests for Identification of Colli Lymphadenopathy Patients at RSPAL. Dr. Ramelan Surabaya. International Journal of Advanced Health Science and Technology, 3(1).
Barsouk, A., Aluru, J.S., Rawla, P., Saginala, K. and Barsouk, A. (2023) Epidemiology, Risk Factors, and Prevention of Head and Neck Squamous Cell Carcinoma. Medical Sciences, 11.
Bhunia, C., Chatterjee, S., Kundu, D. and Bhattacherjee, S. (2022) Comparative Evaluation of Cell Block Histopathology and Conventional Smear Cytology in FNAC of Clinically Suspected Cervical Lymph Node Malignancy. Medical Journal of Babylon, 19(1), pp. 94–8.
Caraway, N.P. (2015) Evolving role of FNA biopsy in diagnosing lymphoma: Past, present, and future. Cancer Cytopathology, 123, pp. 389–93.
Chong, Y., Park, G., Cha, H.J., Kim, H.J., Kang, C.S., Abdul-Ghafar, J. et al. (2023) A stepwise approach to fine needle aspiration cytology of lymph nodes. Journal of Pathology and Translational Medicine, 57, pp. 196–207.
Facciorusso, A., Crinò, S.F., Muscatiello, N., Gkolfakis, P., Samanta, J., Londoño Castillo, J. et al. (2021) Endoscopic ultrasound fine-needle biopsy versus fine-needle aspiration for tissue sampling of abdominal lymph nodes: A propensity score matched multicenter comparative study. Cancers (Basel), 13(17).
Foshat, M., Stewart, J., Khoury, J.D., Staerkel, G.A. and Caraway, N.P. (2019) Accuracy of diagnosing mantle cell lymphoma and identifying its variants on fine-needle aspiration biopsy. Cancer Cytopathol, 127(1), pp. 44–51.
Ghate, G.A., Thomas, J. and Bhat, N. (2018) A Clinico-Etiological Study of Cervical Lymphadenopathy in Otorhinolaryngology Practice. Int J Otorhinolaryngol, 4(2), pp. 51–4. Available at: http://www.sciencepublishinggroup.com/j/ijo
Goyal, S., Resident, S., Jaipur, S. and Kaur Brar, R. (2017) Histopathological and cytological spectrum of lymphadenopathy: a window to preliminary diagnosis [Internet]. Original Research Article, International Journal of Medical Research and Review. Available at: www.ijmrr.in
Hanzalová, I. and Matter, M. (2024) Peripheral lymphadenopathy of unknown origin in adults: a diagnostic approach emphasizing the malignancy hypothesis. Swiss Medical Weekly, 154.
Karaman, S., Uslu, E., Başaranoğlu, M., Kamaşak, T. and Bitkin, E.Ç. (2020) Retrospective evaluation of our patients with lymphadenopathy. Eastern Journal of Medicine, 25(3), pp. 340–4.
Krämer, A., Bochtler, T., Pauli, C., Baciarello, G., Delorme, S., Hemminki, K. et al. (2023) Cancer of unknown primary: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. Annals of Oncology, 34(3), pp. 228–46.☆. Annals of Oncology. 2023 Mar 1;34(3):228–46.
Lee, D.E., Pak, M.G., Kim, S.H. and Chandler, C. (2023) Kikuchi-Fujimoto Disease: A Case of Febrile Cervical Lymphadenopathy With Hematological Abnormalities. Cureus, 23 October.
Lestari, T., Kamaludin, Lowbridge, C., Kenangalem, E., Poespoprodjo, J.R., Graham, S.M. et al. (2022) Impacts of tuberculosis services strengthening and the COVID-19 pandemic on case detection and treatment outcomes in Mimika District, Papua, Indonesia: 2014–2021. PLOS Global Public Health, 2(10 October).
Luo, S., Fu, W., Lin, J., Zhang, J. and Song, C. (2023) Prognosis and local treatment strategies of breast cancer patients with different numbers of micrometastatic lymph nodes. World J Surg Oncol, 21(1).
Malhotra, A., Lahori, M., Nigam, A. and Khajuria, A. (2017) Profile of lymphadenopathy: An institutional based cytomorphological study. Int J Appl Basic Med Res, 7(2), p. 100.
Montégut, L., López-Otín, C. and Kroemer, G. (2024) Aging and cancer. Molecular Cancer, 23.
Preethi, S., Narayanan, N. and Venkatakarthikeyan, C. (2024) A Prospective Clinicopathological Study of Cervical Lymphadenopathy in a Head and Neck Unit of a Tertiary Referral Centre. Apollo Medicine, 21(1_suppl), pp. S88–95.
Pujani, M., Jetley, S., Jairajpuri, Z.S., Khan, S., Hassan, M.J., Rana, S. et al. (2016) A critical appraisal of the spectrum of image guided fine needle aspiration cytology: A three year experience from a tertiary care centre in delhi. Turk Patoloji Derg, 32(1), pp. 27–34.
Rus, M., Popescu, M.I., Ardelean, I.A., Andronie-Cioară, F.L., Bonţea, M.G., Vicaş, R.M. et al. (2024) The role of fine-needle aspiration biopsy in the diagnosis of malignant tumors. Romanian Journal of Morphology and Embryology, 65(1), pp. 81–7.
Zufry, H., Nazarrudin, N., Zulfa, P.O., Sucipto, K.W., Kamarlis, R.K., Ekadamayanti, A.S. et al. (2023) Comparative analysis of accuracy between fine-needle aspiration biopsy and postoperative histopathology for detecting large thyroid nodules: A retrospective observational study. Narra J, 3(2).
Downloads
Published
Issue
Section
Categories
License
Copyright (c) 2026 Zuhdiyah Nihayati, Aditya Sita Sari, Nila Kurniasari
This work is licensed under a Creative Commons Attribution 4.0 International License.
